Are Vectura Group PLC And Circassia Pharmaceuticals PLC Better Buys Than GlaxoSmithKline plc?

Should you add Vectura Group PLC (LON: VEC) and Circassia Pharmaceuticals PLC (LON: CIR) to your portfolio before GlaxoSmithKline plc (LON: GSK)?

| More on:

The content of this article was relevant at the time of publishing. Circumstances change continuously and caution should therefore be exercised when relying upon any content contained within this article.

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More.

Although GlaxoSmithKline (LSE: GSK) (NYSE: GSK.US) has struggled to grow its net profit in recent years, that situation is set to change. Certainly, the pharmaceutical company is continuing to feel the pain of generic competition but, with considerable cost savings to come through over the next couple of years, its margins should pick up moving forward.

In fact, GlaxoSmithKline is set to overturn four years of a falling bottom line to post earnings growth of 11% in financial year 2016. That would be an impressive rate of growth, being around 50% higher than the growth rate of the wider index. And, with GlaxoSmithKline having a price to earnings (P/E) ratio of 16.9, it still offers good value for money for a highly diversified, financially sound pharmaceutical company. In fact, GlaxoSmithKline has a price to earnings growth (PEG) ratio of just 1.4, which indicates that its shares could move much higher over the medium to long term.

Of course, GlaxoSmithKline is one of many impressive pharmaceutical companies listed in the UK. For example, Vectura (LSE: VEC), the biotech respiratory specialist, is also expected to post much-improved financials over the next couple of years, with it set to turn from loss into profit in the current year. In fact, after racking up £48m in pretax losses in the last five years, Vectura is forecast to generate a pretax profit of £2.5m in the current year. And, looking ahead, its pretax profit is set to rise to £20m next year, which is gradually being priced in by the market.

As such, Vectura’s share price has risen by 38% already this year and, despite trading on a forward P/E ratio of 27.6, it still holds considerable appeal owing to a PEG ratio of just 0.2. Therefore, its share price growth could challenge that of GlaxoSmithKline moving forward.

Meanwhile, Circassia (LSE: CIR) is another pharmaceutical company with considerable potential. Its recent share placing was successful and allowed it to make two key acquisitions, with asthma specialist, Aerocrine, and chronic obstructive pulmonary disease stocks, Prosonix, being acquired for around £240m in cash. And, while the market has been rather subdued regarding the company’s progress (Circassia’s shares are up just 7.5% in the last year), Neil Woodford’s 13.5% stake is likely to help investor sentiment to improve moving forward.

Despite this, GlaxoSmithKline appears to be a better buy than both Circassia and Vectura. That’s at least partly because of its stronger financial standing, black bottom line (Circassia is set to remain a loss-making company over the next two years) and the fact that there is a clear catalyst to push GlaxoSmithKline’s share price higher, in terms of its appealing PEG ratio. In addition, GlaxoSmithKline has greater diversity than its two smaller sector peers and, while investor sentiment has been rather weak in recent years, a refreshed strategy and improving financial performance could enable its share to rise rapidly over the medium to long term.

So, while Circassia and, in particular, Vectura, are worth buying at the present time, GlaxoSmithKline appears to be the preferred option.

Peter Stephens owns shares of GlaxoSmithKline. The Motley Fool UK has recommended GlaxoSmithKline. We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors.

More on Investing Articles

Santa Clara offices of NVIDIA
Investing Articles

£5,000 invested in Nvidia stock 6 months ago is now worth…

Nvidia stock's taking a breather at the moment. But it could be getting ready for its next move higher, says…

Read more »

British coins and bank notes scattered on a surface
Investing Articles

I hold Lloyds. Is it madness to buy Barclays shares too?

Harvey Jones is keen to buy Barclays shares but wonders whether he's simply doubling down, given that he already holds…

Read more »

Asian man looking concerned while studying paperwork at his desk in an office
Investing Articles

It’s time we all took a long, cold look at the Lloyds share price

The Lloyds share price has been good to Harvey Jones, making him a huge fan of the FTSE 100 bank.…

Read more »

Warren Buffett at a Berkshire Hathaway AGM
Investing Articles

Warren Buffett didn’t retire early. But could his investing wisdom help you do so?

Warren Buffett's wisdom from decades of stock market investing is actionable even for a modest investor who simply aims to…

Read more »

Young female hand showing five fingers.
Investing Articles

5 compelling investment ideas for a Stocks and Shares ISA in 2026

Edward Sheldon discusses some ideas to consider for a Stocks and Shares ISA and highlights a UK stock that could…

Read more »

Man writing 'now' having crossed out 'later', 'tomorrow' and 'next week'
Investing Articles

Is this the best time to buy shares in a long time?

Earlier this week, Bill Ackman stated on X that this is the best time to buy shares in a long…

Read more »

A senior man and his wife holding hands walking up a hill on a footpath looking away from the camera at the view. The fishing village of Polperro is behind them.
Investing Articles

£1,000 buys 35 shares in an incredibly reliable FTSE 100 dividend stock

Despite falling 72% from their highs, shares in this FTSE 100 company have been an incredibly reliable source of dividend…

Read more »

Warren Buffett at a Berkshire Hathaway AGM
Investing Articles

This is what Warren Buffett has to say about passive income — and I’m listening!

While searching for new ways to earn passive income, our writer takes to heart sage advice from the Oracle of…

Read more »